WHAT IS AUCATZYL?
AUCATZYL is a CAR T-cell therapy designed specifically for you.
CAR T-cell therapy, or chimeric antigen receptor T-cell therapy, is a type of immunotherapy that helps your own immune system fight cancer. It does this by taking your T cells, a type of white blood cell, and putting them through a closely monitored process that transforms them into CAR T cells. These modified CAR T cells are then put back into your body, where they can now target and attack leukemic (cancer) cells.
TREATMENT OVERVIEW
How is AUCATZYL treatment given?
AUCATZYL is different from other CAR T-cell therapies. It is the first CAR T-cell therapy for relapsed/refractory B-cell acute lymphoblastic leukemia (B-ALL) that is individualized based on a bone marrow assessment. AUCATZYL is given in 2 separate infusions, approximately 10 days apart. Your doctor will discuss your schedule with you.
Once you and your doctor decide AUCATZYL is the right CAR T-cell therapy option for you, your blood cells will be collected through a process called leukapheresis. The cells are then sent to a manufacturing center where they will be modified to make AUCATZYL. While your customized AUCATZYL is being made, you may get other medicines to treat your acute lymphoblastic leukemia.
Within 7 days before starting treatment, a bone marrow sample will be done to confirm the level of leukemia in your body. The results of this test will enable your doctor to tailor the dose of AUCATZYL to your specific need.
AUCATZYL is given in 2 separate infusions, approximately 10 days apart.
AUCATZYL is given in 2 doses to help prevent the possibility of serious side effects, and to help the number of CAR T cells increase following infusion.
How will I receive AUCATZYL if my doctor decides it’s the appropriate treatment for me?
AUCATZYL CAR T-cell therapy is available only at Authorized Treatment Centers. Once your doctor determines that you should receive AUCATZYL, they will provide treatment at a certified center or refer you to one.
AutolusAssist™ can help provide you with a Case Manager to guide you through the entire CAR T-cell therapy process.
What happens after AUCATZYL therapy?
Your healthcare team will need to monitor you daily from the time you receive your first dose for at least 14 days. After your first dose, you should plan to stay near the treatment center for at least 4 weeks, so that your healthcare team can continue to closely monitor you.
Treatment with AUCATZYL can cause sleepiness, confusion, weakness, and temporary memory and coordination problems. For this reason, do not drive, operate heavy machinery, or do other dangerous activities for 8 weeks after your AUCATZYL treatment.
SUPPORT & RESOURCES
AutolusAssist is at your service
AutolusAssist is a convenient way to find valuable resources and dedicated support throughout the treatment journey.
Live support is available each time you call: a Case Manager is ready to answer questions that you may have about insurance, AUCATZYL CAR T-cell treatment, and support resources.
Learn more at AutolusAssist.
Contact AutolusAssist for support 24 hours a day, 7 days a week at (855) 288-5227
TREATMENT CENTER LOCATOR
Connecting patients and their caregivers to our CAR T-cell therapy
AUCATZYL CAR T-cell therapy is available only at Authorized Treatment Centers. Enter a location below to find centers that are certified to dispense and administer AUCATZYL CAR T-cell therapy.
Please check this tool often; centers will be added as they become available.
Authorized Treatment Centers are independent facilities certified to dispense Autolus CAR T-cell therapy. Autolus does not verify center licensure, quality of care, or insurance coverage. Contact the infusion provider for verifications.
Here when you need us
For more information about AutolusAssist, call us at (855) 288-5227